Archives for category: Philip Landrigan

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Mount Sinai’s Dr. Landrigan discusses how obesity has become an epidemic within the United States. The rates of obesity have tripled since the 1970s, and this has led to a significant increase in type 1 and type 2 diabetes as obese children are at a much higher risk of developing diabetes.

Dr. Landrigan also provides tips on how to prevent obesity and the diabetes that commonly follows obesity. Studies are being conducted at the Children’s Environmental Health Center to determine whether there is a link between common chemicals and obesity.

To view Mount Sinai’s Children’s Health Campaign containing tips, facts, videos, articles and more on important children’s health issues such as diabetes, autism, asthma, allergies and nutrition, click here.

To view the Children’s Environmental Health Center, click here.

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Mount Sinai’s Dr. Landrigan discusses the rise of autism in the United States. The Children’s Environmental Health Center at Mount Sinai has studied the causes of autism and found that chemical exposures can contribute to autism and other learning disabilities.

To view Mount Sinai’s Children’s Health Campaign containing tips, facts, videos, articles and more on important children’s health issues such as diabetes, autism, asthma, allergies and nutrition, click here.

To view the Children’s Environmental Health Center, click here.

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Dr. Landrigan discusses why the Children’s Environmental Health Center (CEHC) was created at Mount Sinai. Scientific evidence is strong and continuing to build that hazardous exposures in the modern environment are important causes of these diseases. Indoor and outdoor air pollution are now established as causes of asthma. Childhood cancer is linked to solvents, pesticides, and radiation. Furthermore, the National Academy of Sciences has determined that environmental factors contribute to 28% of developmental disorders in children.

The Mission of the CEHC is to address this challenge — to protect children from toxic chemicals in their air, their water, and their food by spearheading efforts to track the root environmental causes of disease. The Center’s research builds on over three decades of work by its director Dr. Philip Landrigan, a renowned pediatrician and epidemiologist who has devoted his career to protecting children against environmental threats to health.

To view Mount Sinai’s Children’s Health Campaign containing tips, facts, videos, articles and more on important children’s health issues such as diabetes, autism, asthma, allergies and nutrition, click here.

To view the Children’s Environmental Health Center, click here.

Daily Green: Wanted: Chemicals that cause autism,

Dr. Philip Landrigan is rounding up a posse in search of one of America’s most elusive evildoers: The cause of autism, which afflicts as many as 1 in 80 American children. Though the soft-spoken, gentlemanly pediatrician doesn’t cut the figure of a sheriff, he used Wild West language to describe the hunt he and his fellow scientists have embarked on.

“We want a ‘Most Wanted Chemicals’ list. We want a ‘Dirty Dozen,'” he told the audience Wednesday at Exploring the Causes of Autism and Learning Disabilities, a conference organized by the Mount Sinai Children’s Environmental Health Center, where Landrigan is dean of global health and chairman of the Department of Preventative Medicine. Landrigan received a 2010 Heart of Green Award from The Daily Green.

Diagnosis of Autism Spectrum Disorder, a developmental disability with a range of effects on intelligence and sociability, increased 57% between 2002 and 2006, according to Colleen Boyle, acting director of the National Center on Birth Defects and Developmental Disabilities. And while the center’s last set of statistics drew alarming headlines about 1 in 110 children now being diagnosed with autism, she said that’s an average; the rate could be as high as 1 in 80 (or as low as 1 in 240).

As recently as 2005, the increase in diagnoses was attributed to just that: An increase in diagnoses. Doctors and parents, it was thought, were more aware of the symptoms of the disease, the definition of the Autism Spectrum Disorder grew more expansive, government services were more widely available and the stigma associated with the illness was disappearing – all of which contributed to an increase in diagnosis that had little or no basis in actual increased illness.

But the rates of disease are actually increasing, not just the diagnosis or treatment of disease, according to research by Irva Hertz-Picciotto and colleagues at the Center for Children’s Environmental Health at the University of California-Davis.

And that’s just one reason genetics alone can’t explain autism. Genetics clearly plays a role – if one identical twin has autism, 70% of his siblings do, too. But even scientists sometimes mistake a genetic basis of disease for an explanation of its causes: the environment is still the trigger for the expression of genes. (And scientists are only now exploring the epigenetics of disease – not just the genes themselves, in other words, but their place in the DNA sequence.)

The question is: What are those environmental triggers that cause autism? And when in the early development of a fetus does the trigger get pulled? The triggers may or may not be synthetic chemicals: Other aspects of the environment that may affect gene expression include nutrients in food, physical factors like heat or radiation, and exposure to medications, alcohol and drugs.

The trigger-happy culprits are on the lam. Landrigan and his colleagues are hunting them down.

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