Foreword (ix – x):

“Curiously, the other common form of diabetes, type 1, also appears to be related to the stresses of the modern world, through a complex process, less well understood, by which the immune system mistakenly identifies as foreign the single hormonal apparatus responsible for lowering glucose levels, the beta-cell of the islet of Langerhans of the pancreas, which consequent disastrous outcome for the person involved. Is this caused by too little exposure to common ingestions of childhood, or too much exposure to processed food (or perhaps even cow’s milk), or to environmental pollutants, or abnormalities of vitamins or minerals, or to genetic imbalances, or to some complex of all of these.”

Prologue (xix):

“So it was from north to south, east to west: the same alarms were being rung, and the same questions being asked, by parents, school nurses, and people with diabetes. Were these clusters of type 1 just statistical flukes, or were they real? If real, was in increase happening in just a handful of unlucky towns, or in many towns and cities, and in every state? What dark force could be behind the rise of such a dreaded, lifelong, life-shortening disease? And what, if anything, could be done to reverse it?”

Prologue (xx):

“Type 1, it’s true, used to be rare. Today, however, it’s about twice as common among children as it was in the 1980’s, about five times more common than in the years following World War II, and perhaps ten times more common than 100 years ago, if early statistics are to be believed. Genes have not changed; lifestyles and environmental risk factors have. Part 2 of this book will explore what those risk factors are. Suffice it to say for now, that while Weston might have“` unique local factors pushing its recent outbreak, it is also emblematic in many ways of the new normal across the United States, and indeed around the world: how we live and play and work, and why that ha made us so curiously susceptible to type 1 diabetes.

Type 2 is also rising, of course, but far faster than the rate of obesity. In fact, the rate of new type 2 cases has doubled in the past decade, according to the U.S. Centers for Disease Control and Prevention. Shockingly, the CDC now projects that 33 percent of all boys and 39 percent of all girls born in the year of 2000 will develop type 2 in their lifetimes.  That’s more than one in three overall. For blacks and Hispanics, the projections are even worse, tipping to over half-53 percent- of all Hispanic women, meaning that more of them will eventually have diabetes than do not.”

Prologue (xxii):

“Now take one final step back and ask yourself: 88 years after the discovery of insulin, with all the dozens of pills available for type 2, all the high-tech treatment of available for type-1, and the estimated $116 billion per year spent on the medical treatment of diabetes in the United States alone, why the heck do more people get diabetes, and more people die of it, each year?”

Prologue (xxii):

“I am happy to report, after spending over a year interviewing hundreds of physicians, researchers, and patients in the United States and abroad, and even participating in a clinical trial, that there is a better way. Flying under the radar of most observers, a number of revolutionary approaches are making quiet, dramatic gains towards preventing, curing, or significantly improving the treatment of diabetes. As we shall see in Part 3 of this boo, none of them involves lecturing people about the need to eat less and exercise more. None of them requires diabetics to test their blood sugars more often. And none of them places the blame for the disease and its dire consequences in the laps of diabetics. Instead, an astonishing body of evidence has built up in support of an interlocking group of theories, provocative as they are disturbing, as to why both type 1 and type 2 diabetes are rising in lockstep and how we can, for the first time in history, prevent or cure both of them.”

Prologue (xxiii):

“To appreciate just how bizarrely unnatural the current mushrooming of the disease has become, it is useful to go back to a time when doctors could go their entire careers without seeing more than a handful of cases, or any at all. Part 1 of this book will narrate the biography of a disease called diabetes: how it started small and grew into a moster.”