From Chemical & Engineering News:

Bisphenol A—an estrogen-mimicking chemical found in baby bottles, food containers, and household electronics—has been linked to a host of health problems in animals and people. Now researchers have detected it in the environment and urine of young children, revealing that preschoolers absorb BPA primarily through the food they eat.

Manufacturers use BPA to make plastics and epoxy resins, and BPA can leach from products containing these materials into food, beverages, dust, and air. Numerous studies, mostly conducted on animals, have linked high levels of the endocrine-disrupting chemical to conditions such as cancer, obesity, heart disease, infertility, and neurological disease.

Although scientists think that developing organisms are the most susceptible to BPA’s potential toxic effects, few studies have examined BPA exposure in young children, says Linda Sheldon, associate director at the U.S. Environmental Protection Agency. So in 2000 and 2001, Sheldon, Marsha Morgan, an EPA research scientist, and their colleagues joined forces to measure children’s exposures to BPA and other chemicals in an EPA study called Children’s Total Exposure to Persistent Pesticides and Other Persistent Organic Pollutants (CTEPP). They collected samples of solid and liquid foods, air, dust, and soil from the homes and daycare centers of 257 children between the ages of 2 and 5 in North Carolina and Ohio.

. . . . The researchers showed that the children’s solid and liquid foods contained the highest amounts of BPA. However, says Morgan, “at the time we collected the samples, we weren’t able to quantify BPA in urine with existing analytical methods.” Scientists at the U.S. Centers for Disease Control and Prevention developed a mass spectrometric method to do just that, so Morgan and Sheldon sent a subset of frozen urine samples to CDC scientists for analysis.

Consistent with studies done in other countries, the researchers detected BPA in all of the 81 urine samples from preschool-aged children in Ohio. However, even the highest urinary BPA concentration measured, 0.21 mg/L, was well below the maximum level EPA considers safe: 2 mg/L BPA in human urine. The researchers used statistical analysis to show that the children’s excreted amounts of urinary BPA correlated with the doses they received through their food. The team discovered that dietary ingestion accounted for more than 95% of the BPA excreted in the preschoolers’ urine.

[Upstream Expert] Carlos Sonnenschein, a cell biologist at Tufts University School of Medicine, commends the researchers for their “rigorous experimental approach.” He says, “I consider this paper of great importance because it conveys evidence necessary for public health officials and politicians to react” and develop regulations that will keep BPA out of food.

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